How bullet proof is Toyota's 3.5 V-6?

My brother has a 3.5 in his '21 Camry. He bought it new and it already has +45k miles on it. It shouldn't take long to get a 100k mile report. Amsoil and Wix XP filters, 10k OCI.

He's already put on a set of tires:

View attachment 156667

Historically, he drives his Toyotas (Tercels, Corollas) +400k miles.
What the heck happened to that tire?
 
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