Best: 2019 Fiat Spider, 37 mpg easily, 2-3 higher if I drive it like a normal human being on flat roads. Tuned, aftermarket exhaust, most fun I've ever had with any car. Drive it all day long, the gas gauge just never moves.
Worst: 2001 Sequoia, 15mpg coasting downhill with the engine off and a hurricane tailwind. It wasnt this bad when we first got it, it would get 18-20 pretty consistently on the highway. The cheapy replacement Autozone O2 sensors really killed the mpg, but since we only use it in winter or hauling stuff, its not worth spending more money to save 2-3 mpg
Worst of the worst worst worst: '77 Mustang II that I had in high school in the early 80's. A 302, 2bbl, automatic, and whatever high ratio rear end the previous owner put in it... Full tank would last maybe 90 miles....maybe. I could sometimes get it to 100 miles if I drove it very, very gently, which I rarely did. It was pretty horrible, but it was in nice shape and the performace was quite impressive, especially considering the era, and I had a really good job in high school so I didnt care about the exorbitant gas bill due to the extremely frequent fill ups. If I had a brain I would have bought a junkyard rear end and put it back to stock. Overall reliability-wise the car was a serious turd but it had some serious giddy-up.