First time I tried it was in my 1992 Subaru Loyal. Was conventional, probably 10w30 or 10w40, maybe both at different times. Seemed to work fine. Then I bought a 97 Sonoma (4.3 V6) from a buddy, he ran the first 92k miles on Mobil1 5w30. I continued with that for a while, but eventually switched to ST syn 5w30 (at probably 125k miles) and continued running that until I traded it in at 198k. (6k mile OCI the entire time) That engine was still running great. The new ride was a 2005 Colorado with the 3.5 I5 engine. Ran ST syn 5w30 for quite a while, then started switching back and forth with Formula Shell syn 5w30. I would guess I used about 50/50 between the Shell and ST over the years. I bought it with 6,250 miles, and at about 190k it started to puff blue smoke upon startup if I had driven about 30 minutes of highway prior to shutting down, the next 2 fills were PP 5w30, seem to clear up that problem with the smoke. (probably a dirty PCV or something) I ran 7,500 mile OCI for the life of that truck. Sold to my brother-in-law almost a year ago (at 204,400 miles), he drives it out to and around the farm and loves it. I now have a '16 Sierra, and I've performs 1 change, it's now full of ST 5w30 Dexos1 gen 2. Plan to keep using that whenever the OLM tells me to change it, for the foreseeable future.
My wife's Altima is currently filled with ST 0w20 syn. Plan to sell that as soon as spring hits, her late mother's Volvo s60 is in the garage ready to take over the job. No ST for that s60, however, because it requires 5w30 ACEA A5/B5.
Our '99 s70 gets whatever 10w30 is cheap. It's had a LOT of ST, both syn and conventional over the past 262k miles. It's next change with be Harvest King, I just discovered a local farm store that carries that for $1.99/qt.