After wrestling a spark plug for an hour on my mom's 1970 Mercury wagon back in the day (the plug was a ceramic-free pretzel by the time I got it out, and I think a small chunk of insulator dropped into the hole in the process), I swore a blood oath that I'd NEVER install a plug without anti-sieze again. I know some plug manufacturers' websites say, "Don't use grease...it can interfere with the plug grounding properly." But me not care....I never want to pull out a preztel plug again, and have never had any issues with using anti-seize since then.
Another matter.... Many lubricants state "...and Penetrant" on the label, such as the Liquid Wrench that ultmately removed this Tundra's plug. I've never given that a boatload of thought, but perhaps that's the key here -- look for "penetrant" on the label, since perhaps that's actually a measurable quality that can be intentionally formulated into a product.