I've never personally ran McAfee, but years ago I remember it having a lot of issues. The main issue being the program using up a lot of resources on your computer, and it would bog everything down. Otherwise, from what I've read/heard, it's considered to be pretty useful in recent times.
I used to run ESET Nod32 for years, and it was one of the best anti-virus programs at the time (in my opinion) as it ran quietly in the background and caught anything malicious that attempted to save data to my computer. It even caught files that I downloaded on purpose and knew were fine, it would just put them in quarantine since it had a trace similar to that of malicious files.
Norton is typically renowned as the "best" by many, although you have to update your subscription each year.
AVG is average at best.
Panda Anti-Virus used to be very good as well (although most people have probably never heard of it), but it can be somewhat of a resource hog.
I used to run ESET Nod32 for years, and it was one of the best anti-virus programs at the time (in my opinion) as it ran quietly in the background and caught anything malicious that attempted to save data to my computer. It even caught files that I downloaded on purpose and knew were fine, it would just put them in quarantine since it had a trace similar to that of malicious files.
Norton is typically renowned as the "best" by many, although you have to update your subscription each year.
AVG is average at best.
Panda Anti-Virus used to be very good as well (although most people have probably never heard of it), but it can be somewhat of a resource hog.