I guess you need to qualify what kind of flush. Chemical or water. With a water flush you just need to get out (or best to) all the water from a garden hose. With a chemical flush you need to get out all traces of the flush chemical and any water from a garden hose.While this is true, a '15 Ford probably started life with the Motorcraft orange OAT coolant and now many are switching to the Motorcraft VC-13-G Yellow P-OAT.. though it's supposed to be backwards compatible, but I'd rather get all the old orange out... it is now 8 yrs old if the factory fill.
I will be in the same boat as you in the not too distant future. My 2015 PSD had the Ford orange coolant replaced with new Ford Orange coolant. But the next radiator service will be to Ford Yellow. And the PSD had two separate cooling systems.