Cameco, the world's largest Uranium miner.
Hitachi's only plant outside Japan although it just closed; made generators for power plants. Cool thing was they had to construct one or more unique rail cars for each generator. About one in three new generators installed in power plants in US / Canada / Mexico since about 1980 came from the plant here (competitors are GE and Siemens). The plant, which features the largest machining and fabrication equipment in Canada, will be reborn by new owner Brandt Industries, whom are a Heavy Equipment manufacturer and reseller in Western Canada, but won't result in a "Global Brand' like Hitachi was. 400 people were laid off from Hitachi, and Brandt will hire 500 for the 21- acre complex.
But the one that probably fits the OP's question best would probably be DraganFly Innovations, who have been selling Unmanned Aerial Vehicles (drones) for more than two decades to Law Enforcement, Security, Film, Safety, and other industries. Founder Zenon Dragan still runs the company from here. Popular Mechanics (2008 "Best of What's New") ABEX award, MIT, Vanderbilt University, NBC, Walt Disney Company, United Nations, the FAA uses them as their test platform (it is certified for night operation and has a US nationwide FAA COA (largest number of deployed FAA approved UAS's operating in the US), Canada SFOC approval, a number of the world's military's and border / prison / security agencies.