We had a 2004 Escape Hybrid go to 190K in our fleet before it was phased out. Even with the higher mileage, it was a popular choice. That being said, it was not a trouble-free 190K. It was prone to a lot of brake/regeneration issues. The rear-diff went sour, and had some electrical troubles. It was one of the highest cost-per-mile vehicles I had in the maintenance department, but it was popular... compared to the minivans in our fleet.
I thought it was a horrific riding car. It was uncomfortable within 15 minutes, unbearable in 30. Highway noise (tire roar) was terrible and for some reason, it was prone to a lot of high-speed vibrations we always struggled to track down. Ride was bouncy/jittery which lead to another issue...
It was my "assigned" winter weather '4WD' car and it stunk in the snow/ice. Dynamically, it was just off on the white stuff and prone to letting its rear-end come around even with snow tires. So it was a jittery mess when it was dry and warm... take away traction and it was down-right scary for a 4WD vehicle. It might do better in mid-western flat and snow, but mountain snow was beyond its reach.
The only redeeming quality is that it was a good training vehicle for winter driving because I could get it to do the "bad" winter dynamics very easily. It punished mistakes very well. Oh, and it was fun to break the rear-end out in a roundabout for some tomfoolery too.
My synopsis is this: Popular but bad, dangerous in winter for the mountains.