I think the manufacturers state don't use any additive EXCEPT "our (approved) additives." (e.g., GM has limited use additives). Mmmm, you could also go strictly by the manufacturer's sticker in the door which indicates what air pressure you should use in your Ford Explorer with its Firestone Tires. (Ford's under-pressure guidelines may be partially responsible for the accidents). Don't mean to flame, but car makers, oil refiners, et al, are most concerned with their best legal/profit interests, not necessarily ours. When you say "might change the chemistry for the worse," that is probably a true evaluation of the manufacturers' fear of the unknown. On the other hand, I can't think of a single other product that uses more different parts and chemicals - from different suppliers - that an American-marketed vehicle. So, its a "selective" fear.