From my drag racing days I remember the guys who built Alcohol cars. They had to run huge jets in the carbs because the alcohol as we all know, requires more fuel:air etc. But as a result, they had to change their oil after every night of racing. They all said the same thing, "...the inside of the engine gets full of sweat and moisture after every race.." When they pull the valve cover off to make valve adjustments, the bottom of the cover is soaking wet and water running down mixing into the oil. Something to do with the bigger volume of fuel rushing through the engine is absorbing a LOT more heat and causing the engine to be what they considered "ice cold".
That example is a pretty extreme environment with engines making more than a thousand horsepower, but you get the idea. On a street car driven normally, the intake system and cylinder heads will run cooler than normal. Some engines won't be affected as much depending on how great the pistons fit when cold (ie: hyper-eutectic vs forged), some engines by design have a very hot intake area with heavy iron heads, those probably won't be affected too much either.
Either way, Ford spent millions of dollars doing their research, I've only spent a few hours looking at a computer- I'd say Ford knows best when they recommend early oil changes when running E85.