I switch back and forth between synthetic and conventional on a seasonal basis with my semi with a Detroit Series 60. Synthetic in the winter for better cold flow performance (it sits during break periods with engine off and no ability to plug in), conventional in the summer to keep costs down. When it take 10 gallons for a oil change, every little bit helps. I have run samples on both in the same engine and I have noticed no difference in oil sample results one way or the other using the same brand of oil, which in my case, is Chevron Delo for the same OCI.
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