I went with Revos on the 2wd jeep. I gave the Destination ATs a good, hard look, but since I am limited to 2wd went with the more aggressive revo. I do "play" from time to time and dislike getting stuck. If it weren't for that, it would have been the AT's, hands-down.
That said, the Rav-4 is a probably a little lighter on its feet, so for snow traction the Destination ATs may not bite as much as REVOs. But, the Rav has engine weight over the drive wheels, an advantage.
For snow, a heavily siped tire will give more bite more than big tread blocks, which is how the Michelin LTX M&S tires do so well. The Goodrich Traction TA's do pretty well as well in the snow-- we had them on a crv, but Dueler HL's outdid those in the dry (never had the HLs in the snow).
Revo's eat mpg... it's all over the reviews, and my personal experience is the same. They put enough of a drag on the car that the trans actually hunts more for gear. NOT a tire for mpg.
So--- in my mind the Destination AT wouldn't be a bad tire at all, though you do have other options. Also compare to the Destination LE.... I've had 2 sets, including a brand new set on the wife's MDX. It's a very good tire for not a lot of money. Our first set this go-round had a flaw... the tread "walked" and on one, and on my second return to the shop they replaced all 4 under their 30-day satisfaction guarantee and this set has been great. That guarantee is nice.
But, they will not compare to a snowflake tire-- and if the rubber is too stiff for the weight on the vehicle may not be optimal in snow, but IMO it's a good tire. It may handle a little firm, which is subject to your tastes.
M