I completely agree that synthetics offer some advantage in fuel savings.
The problem is that for most people, driving is such an erratic event. I'm not talking about road-rage, but just the variability of daily routine driving. You'll never idle, accelerate, pass, be passed, drive up/down the same hills, the EXACT same way each time, with the exact same route with NO deviation for EVERY tankfull. So you have very little true frame of reference to make a call. If you put synthetic fluid in the rear diff, you're likely to get some benefit, but it will be masked by the variability of daily life.
The savings can be shown in static, controlled experimental environments. And the implication is that the savings can be transfered into typical daily use.
If you take each fluid, and take the claims of several lubricant manufacturers, you'd be suprised what is "possible". But there is a big difference between "possible" and "probable". Consider a fuel savings of 3% with synthetic diff fluid, 3-5% for engine oil, 2% for tranny fluid, and who knows what for synthetic grease in the U-joints ... it all adds up quickly.
Unfortunately, the "math" and reality don't always ring equivilant in concert. If you use synthetic fluids throughout, you could THEORHETICALLY get around 8-9% savings, but the reality is that it isn't near that much. Plus, some vehicles already come with synthetics and/or low viscosity fluids, so there isn't really anywhere to move towards. Consider the newer Corvette's. They come with Mobil 1, DEX VI, and the GM grapejuice diff fluid. That's all either synthetic stuff or low vis stuff, straight from the factory. So there is no savings to move towards.
Overall, you'll gain some small fuel savings if you convert the diff fluid to synthetic, but it'll not be enough to convince you one way or another if it was worth the effort. The main benefit to synthetics are extended service life and some ability to negate temp extremes better than dino fluids.