Take your F150 north to Schmid's Auto Body in Syracuse, NY or west to Maag's Auto Body in Sandusky, Ohio for a Rust Check application.
Doesn't matter what you drive if you don't take the proper preventative measures to alleviate rust, it will get a foothold.
I received a letter from Toyota that they are offering a free application of a "corrosion-resistant compound" to the frame of our 2002 Sequoia for vehicles registered in: CT,DE,IL,IN,KY,MA,MD,ME,MI,MN,NH,NJ,NY,OH,PA,RI,VA,VT,WI, & WV. They require two days and will give a loaner during that period.
I'll hold off 'til the Spring to have it applied by Toyota because the Rust Check application I had done 2 years ago is still sloshing around in paneling and subframe last I checked. It's only been treated with Rust Check once. No rotten, rusted frame this vehicle and I have seen some pretty bad Sequoias/Tundras.
Likewise I have seen some BADLY rusted 3rd generation 4Runners but our 1997 4Runners underchasis is pristine. It has only received 2 Rust Check treatments in its lifetime.
Both vehicles have been driven coast-to-coast and up to Canada during the harshest winters through salt-covered roadways. I'm planning a road-trip to Alaska w/ the 4Runner to look at some prime salmon-fishing real estate in the near future. My point being our vehicles have seen the worst of brined-roads and have yet to have any rust on the subframes.
Depending on how long you expect to keep your F150, I'd get the rust problem addressed promptly.
Good Luck!!