If you are using pump gas, it's very likely that you will notice differences between batches of gas.
Ethanol content alone can vary your air/fuel mixture considerably. Couple that with other seasonal fuel changes, and you might notice significant differences. I've stopped using pump fuel in my OPE. I now use 100LL Avgas in some applications and 90 octane recreational fuel in everything else.
Also, I use VP C9 storage fuel in my fire pump. As it does not see regular use and C9 never goes bad. C9 is 96 octane unleaded race gas and storage fuel. It's awesome stuff.