The code reads random misfire, I think it can't detect which cylinder because it's pretty severe. I looked at it with a mechanic I know and he thought it was coming from the #2 pot as well.
I pulled the #2 plug and swapped it with a known good on that cylinder to rule out the first and most obvious potential source of the problem, I am going to put all matching OEM plugs in.
The plug I did pull from the number 2 cylinder (where the noise seems to be eminating from) showed some browning on the ceramic near where the wire connects and there were signs of arcing on the connector for that cylinder's coil. I took out other plugs (cylinders 1, 3, 5) and they appear to be fine. The plugs I had in are Denso Iridiums with less than 15,000 miles. The plug was clean but showed signs of fuel wash.
I am really confused because I started it and drove it in the morning and it ran absolutely fine, let it sit parked all day then as soon as I started it again there was a major misfire.
I will change the fuel filter, change the plugs, check the wires (wires were new with plugs), and start troubleshooting from there. I think/hope it is just a bad coil.