If this loose connection is at a low point in the system, it is indeed by design.
I have heard stories of the Ford system accumulating water condensation in the bottom of the intercooler which can be ingested into the engine with serious results. I think some have actually drilled a pinhole in the bottom of the cooler to prevent this.
That problem did exist in the Ford setup, but I believe it was corrected for 2017 model year forward.
As far as the GMC is concerned, yes it is at a low point in the turbo high pressure intake air system. My former wife's 2005 volkswagen tdi diesel (pump duese unit injector type known as a PD) had a similar o-ring sealed boost hose feeding into the intake manifold with similar slop in the fit and those were known to eventually wear down the two nubs the clamp secured onto and leak air. If not replaced they'd eventually blow clean off of the manifold.