Guys, I have burned more fuel in two strokes than probably all of you together, not being C**ky, I have burned 1000's of gallons. 20:1 30:1 40:1 50:1, and yes, AMSOIL at 100:1 a lot of AMSOIL at 100:1! all my friends and I ran AMSOIL at the race track and in the desert, in the high desert, 4k 5k elevation mountains, always 100;1. None of us seized! Cr250's, yz250's yz490's. AMSOIL was a different animal! We stopped using it about late 80's because we could no longer get it from our supplier. We were bummed, because my yz490 went 2/3 days without fouling a sparkplug. The 250's could usually make it 3/4 days on a plug back then. This was before watercooling and powervalves mind you. We all then switched to Golden spectrol 50:1, None of us had seize issues with that ratio and that oil either. We all had about the same plug life as for fouling goes. We ran a lot of race fuel also. If we ran 40:1 we had fouling issues! A large part of avoiding a seize condition is a proper tune, if you tune your motor for full power, full rpm, lean it out properly so it rev's up tight, but not too tight! And you ride it like mad man after it is properly warmed up, it won't seize. There is no need to run 40:1 and have excessive tail pipe smoke on a two stroke. Your plug should look like a coconut, if it smokes badly, the plug ain't gonna look like a coconut, and your motor ain't gonna make its full potential power.
My expensive Stihl chainsaws use Stihl silver bottle synthetic at 50:1, 13700k, 14000k out of cut, 10000k, 9000k in the cut, none of them have ever seized, and they have a lot of hours on them, and they are highly modified. I have a wireless tack to tune my saws, so my rpm #'s are not just pulled out of thin air.