I contacted Castrol about this, and here was the reply:
Thank you for contacting Castrol North America.
Castrol TranSynd is designed to be suitable only for Allison and GM transmissions requiring DEXRON-IIIG or previous DEXRON type fluid. Castrol TranSynd does not meet DEXRON-VI specifications therefore this fluid is not recommended where DEXRON-VI is specified.
Castrol Transmax DEXRON-VI ATF and Castrol Transmax Full Synthetic Multi-Vehicle ATF fluids are certified and approved by General Motors for all cars and trucks that require DEXRON-VI.
Castrol Consumer Relations