Absolutely!
I knew a family with two daughters. The father was tall & lean, with dark brown hair, brown eyes & chiseled features.
The mother was short & rounder, with blue eyes & natural blonde hair, & a round face shape.
I once dated the elder of the two sisters. She was tall & beautiful features like a model, Brown hair & brown eyes, very striking in appearance & obviously her father's daughter.
Her younger sister had blonde hair & blue eyes & was much more round & sort of plump. Honestly, you couldn't possibly guess the two of them were sisters. The older one resembled her father & had almost none of the physical features of her mother. The younger one was the spitting image of her mother, & had almost no physical features at all of her father.
Genetics is a funny thing… My brother & I look absolutely nothing alike, either.