That is, do not buy E85 for your FlexFuel vehicle, unless you have a nearby steady supply of E85 to feed your new habit. Of course, I'm speaking strictly for myself and my '14 F150 with 3.7L V6. I tried E85 as an experiment...a goof maybe...but the joke was on me. My truck absolutely loves it, and runs with a whole different personality. Throttle response is up, trans shifts quicker...it's truly like a different vehicle. Even going back to 93 octane gasoline is not enough to make the same difference. My problem, in a nutshell, is that the nearest station I can get it is 1.5 hrs away. Fortunately, my work takes me past it often...but not often enough.Now, admittedly I am running a 5Star 87 octane performance tune, so that may allow the truck to better take advantage of these benefits. Yes, I lose a hand calculated 3mpg ( I calculate every tank of every type of fuel), however, when comparing to the next best option of 93 octane, the price break is $1 a gallon ($2.03 E85 vs $3.09 for 93) I'll take that loss. All political aspects/opinions aside and speaking strictly from a performance standpoint, I wish more stations carried it....moral of the story don't try it unless you can support the habit. Drive safe !