There is no yes or no answer. It depends on the machine, what injectors are in it and the environment it lives in. I do a lot of marine engines, the outboards the gas canners have get messed up in a short time, engines operated in the middle east where they fuel can be low quality may need a cleaning often.
If you use top tier fuel and a does of PEA cleaner once in a while you are probably okay until there is an issue. DI is a whole different story.
Edit: You have a decent Bosch injector in the 5.0, they are not trouble prone.