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The gun that I'm drooling over is the Sig P320. It feels well in my hands and isn't too heavy, like some Sig. Haven't fired it, but people say it is very accurate out of the box and very reliable. My 2nd choice is one of the Rugers. I like the Sec9 just for the price tag alone. Usage will be mostly range time and for home defense. Might consider carrying in the future.
The P320 is a great choice. I've fired them a few times and a buddy of mine has owned one for years, nice guns. They also come in a carry platform. If you are thinking of carrying in the future, check that out. IMO, the regular P320 is way too bulky to conceal carry.
Cool thing is if you do get a full size P320, you can always swap out the trigger group in your P320 to a smaller frame for carry, they are fully modular. The serial number is attached to the trigger group not the frame like most handguns. You can swap it into any P320 frame, very neat.