I'm running a 1 micron hydraulic filter for fuel (Fleetguard HF6604, 1u @ 95%, 3u @ 98.6%, and 5u @ 99.5% and those are at 39.6GPM)...I change it once a year with almost 50k miles on it (and there is NO pressure drop in that length of time)...at say 18mpg, 50,000 miles / 18mpg is almost 2800 gallons of fuel filtered...
Racor makes some good filters (they have a 1 micron), and the cat filters are very good with no pressure drop (mainly because they are BIG)...I have seen a lot of these installed in Dodge trucks with Cummins and I have never seen a reported pressure drop...
steved