My house near the water? Heck no.
My inland house in horse country? People run full-out repair businesses out of their home. I have a neighbor who subs out 5 or 6 boats a month to me from his home marine repair business when it's too tough to handle. There's home body shops, performance parts dealer/installers, welder/fabricators, powdercoaters, 4x4/off-road customizers, OPE repair operations, diesel truck repair operations, quad/dirtbike/motorcycle/UTV repair operations.
As we are in horse country, in a very "mind your own ____ing business" part of the county, commercial/agricultural/animal zoning/licenses are a given. Long as the government gets its property taxes, they really could care less what we're up to.