Every 3-4 years or around 45-50k miles, whichever comes first. They are usually worn down by then. I have 42k on my current tires and they have 3/32 on rear and 4/32 on front. They'll be four years old this December. They wore pretty quickly the first 32nds but now they're in the "wearing like iron and refuse to die and getting loud" phase of their life.
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