There are many excellent oils; lots of them.
The issue is this:
are you picking a lube and trying to cram it into some preconcieved notion of use, or are you being pragmatic about the OCIs and going to select a lube that performs well for the lowest cost?
As I understand it, the VBPE is a group II+ and III blend, with a lot of VIIs. Sound familiar? Think T6.
If your OCIs are going to be normal to moderate (and with the 6.0L I think that's a good route to choose), then you don't need a syn by any means. You can easily get some 10w-30 HDEO in conventional form, and you'll find the 6.0L does extremely well; just look at the UOAs from roadrunner as evidence among others.
Sure the VBPE will work fine. But why pay for more if you're not getting more results? At 5-7k miles OCI, you'll never recoup the cost of the syns.
For that matter, the dino 15w-40s work well too, but they will shear. However shearing does not directly equate to wear degredation, despite the predominant fears.
PS - no, you don't need a syn in Baltimore. Don't start whining about how "cold" it gets, because the temps there are well served by conventional oils.