Can't speak for the Versys, but I purchased a used 2008 V-strom 650 six months ago and LOVE it. I have owned probably 30 motorcycles and ridden many more; this bike is definitely in the top 5! This bike was outfitted by prev. owner with Happy Trails panniers, Sargent seat, and a bottle opener on the fork, MadStad windshield bracket with Parabellum shield plus a bunch of other stuff. Added heated grips and lowered the bike since I am 5'5". One of the easiest bikes to jump on and ride, loves the twisties!
Other bikes owned for reference (Honda Interceptor, Suzuki Bandit 1200, Yamaha V-Star 1100, Harley Sportster 1200, Harley SuperGlide and others)
Took it on a 700 mile trip and it runs the Interstate fine at indicated 80mph (actual speed 73 per GPS). I was loaded down with camping gear at the time including stove, lantern, food for 3 days, chair, tent, fishing gear etc). One of the only negative comments would be that it doesn't like cross-winds or riding behind transfer trucks. My saddlebags are HUGE and slab-sided which don't help cross-wind situation, it's not as bad with bags removed.
It hits a real sweet-spot at the aforementioned 80 mph indicated - Quiet, tranquil air and just motors on.
Huge gas tank, good for 250 miles. Like many Japanese bikes the air filter is a royal pain to get to. Have to disconnect half of fairing, gas tank, raise tank (may as well remove it) etc. No dipstick for oil check, has a sight glass that needs a friend to check or a telescoping mirror.
Hope this helps.