I can cause harm if used in too high of a concentration, as too much gunk will build up inside the combustion chamber. I think a ratio of 400:1 to 500:1 is a range to play with, just my personal findings. I would use a product like amsoil Interceptor 2-stroke oil, it is a TC-W3 oil, but with potent detergents over their other 2 stroke oils.(Which might be important for the DI Injectors) Don't use their Dominator, as it is meant to run in a high powered high heat racing applications because if you use it in lower powered lower heat apps, it will not completely burn and build up, it has more anti friction and anti scuff additives.
IMO, Amsoil Interceptor is right at the top with the best 2 stroke oils, but it cost less. Try it.
There are 2 stroke engines now that run at 200:1 that have what is considered super clean emissions, but only running a quality synthetic 2 stroke.