Well, since I own a high mileage car (180k), I know what automobiles are capable of. Granted, I purchased this one new. If I knew a vehicle's previous owner and history, it would not bother me as long as it is priced accordingly. Risk/benefit, higher miles equal higher risk, benefit of lower price for taking the risk.
2005 Dodge Gr. Caravan (180k, 3.8)
2009 Chrysler T&C (66k, 3.8)