It depends on the car. My 2003 ION had a noticeable drop in performance at 60,000 miles, and that was with ACDelco double platinum plugs from the factory. I had no OBDII codes, but the engine definitely ran badly. The manual said those spark plugs should only be changed at 100,000 miles!
When I ordered replacements, ACDelco iridium was all I could get. They must have decided to reduce the number of parts in their catalogs.