Yes, LC can be used in synthetic or conventional oil. Many belive that LC is not needed in Redline due to it's natural oxidation resistance and solvency. THe high ester content in Redline is responceable for botrh these qualitys. I do not see where it would hurt anything. In some Toyotas Terry Dyson has recomended some LC in conjuction with Redline. I plan on usesing a fairly conservative treatment rate though. Conventional and PAO oils benfit the most from LC because they either lack antioxidents or solvency and sometimes both.
P.S. I almost forgott LC depolarizes those VII molacules that would normaly form sludge.