I have been using RedLine SL-1 fuel treatment for a while now, and I can tell that he 3.4 L engine in our 2001 Impala with 68K miles on it idles smother, accelerates smother, and just seams to run and respond to the throttle smother and better. Also saw MPG's go from 14.5 to 16.5 on average here driving mostly 35 MPH in the stop and go traffic up and down the hills in this area.
I talked to the rep at RedLine and per his recommendation I ran one bottle of SL-1 in a full tank of gas. Ran that tank until it was down to 1/8. And now I use a 100 ml graduated plastic measuring cylinder that I perched from McMasterCarr , to measure 4.45 ml of SL-1 per gallon of fuel, and add that at the gas station just before each fill up.
Toward the end of the second bottle of SL-1 I noticed the engine running smoother. Now that I am on the 4th bottle of SL-1 the engine definitely runs smoother.
SL-1 is pays for itself and then some with the increase in MPG's.
You can get it at Pep-Boys.
The down side to using it besides having to add it at every fill, is that it is an oil that seams to get all over your hands, and then anything you touch, and if you get it on your coat, or clothes it does have a noticeable smell, not that bad of a smell, but you will have to wash any item it gets on to get rid of it.
I use old grocery store bags as disposable gloves and throw them away at the trash bin by the pump.
Also SL-1 is very hygroscopic. I think that has something to do with its ability to be usable for storing fuel. If you store the 100 ml graduated cylinder upright, the next time you use it there will be about a quarter of an inch of water in it from the water that the film of SL-1 pulled out of the air. So I store the cylinder upside down in a few old grocery bag in the trunk side compartment between the carpet, and the sheet metal of the back side of the car.
I used Sea-Foam in the past, and think SL-1 is a better fuel system treatment. If it was not such a mess to get on your hands it would be perfect.
An alternative might be to just throw a bottle of SL-1 into a tank of gas every 1 K miles or so, but I do not know if that would get you the same improvement in MPG's.